Molecular Mechanisms Underlying Bacterial Persisters

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Molecular Mechanisms Underlying Bacterial Persisters

All bacteria form persisters, cells that are multidrug tolerant and therefore able to survive antibiotic treatment. Due to the low frequencies of persisters in growing bacterial cultures and the complex underlying molecular mechanisms, the phenomenon has been challenging to study. However, recent technological advances in microfluidics and reporter genes have improved this scenario. Here, we su...

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ژورنال

عنوان ژورنال: Cell

سال: 2014

ISSN: 0092-8674

DOI: 10.1016/j.cell.2014.02.050